Genetic regulation of the vascular endothelial growth factor receptor 1 during sepsis and association with ARDS susceptibility
Eva Suarez-Pajes, Nick R. G. Shrine, Eva Tosco-Herrera, Tamara Hernández-Beeftink, Luis A. Rubio‐Rodríguez, M. Isabel García-Laorden, Almudena Corrales, Miryam Prieto-González, Aurelio Rodríguez, Demetrio Carriedo, Jesús Blanco, Alfonso Ambrós, Elena González-Higueras, Elena Espinosa, Arturo Muriel-Bombín, , Carlos Flores
This study identifies pQTLs of sVEGFR1 levels during sepsis and links them to ARDS susceptibility and mortality using GWAS, colocalisation, and Mendelian randomisation.
medRxiv · Jan 30, 2025 · PreprintGenetic & Genomic Medicine