Aging compromises Zebrafish caudal fin regeneration by disrupting Regenerative gene networks and Cellular metabolism
P V Anusha, Qasid Ahmed, P V Athira, Anushka Arvind, Izzath Fathima, P S Basil, Mohammed Ghalib Enayathullah, Mundhir Mohammed, Ifra Iyoob, Sarena Banu, Jessica Bharathi, Sirin Bano, Saloni Garg, Jameela Bano, Samreen Fatma, , Mohammed M. Idris
This study shows that aging impairs zebrafish caudal fin regeneration by disrupting gene networks and cellular metabolism, with mitochondrial dysfunction playing a key role.
bioRxiv · Mar 26, 2026 · PreprintDevelopmental Biology