Quantifying the contribution of genetic variation to healthcare expenditure across diverse healthcare systems
Sebastian May-Wilson, Jiwoo Lee, Tomoko Nakanishi, Camiel M. van der Laan, Ioannis Louloudis, Kuang Lin, Stavroula Kanoni, Patrick Fahr, Anne Richmond, Chadi Saad, Penelope A. Lind, Zaina Al Kanaani, Mykyta Artomov, Karina Banasik, Enda M. Byrne, , Andrea Ganna
This study identifies genetic variants associated with healthcare costs across multiple systems, finding polygenic influences and large effects from specific loss-of-function variants.
medRxiv · Jul 15, 2026 · PreprintGenetic & Genomic Medicine