Plasmatic immune extracellular vesicle profiles identify prodromal and early stages of Parkinson's disease
Elena Vacchi, Jacopo Burrello, Alessio Burrello, Sara Bolis, Iñigo Ruíz‐Barrio, Ilaria Bertaina, Luca Baldelli, Maria Giulia Bacalini, Giacomo Chiaro, Rudolf Kaelin, Ankush Yadav, Sandra Pinton, Alberto Romagnolo, Simona Vittoria Maule, Sandra Hackethal, , Giorgia Melli
The paper identifies distinct plasmatic immune extracellular vesicle profiles associated with different stages of neurodegenerative proteinopathies, with the highest diagnostic utility for prodromal REM sleep behavior disorder.
bioRxiv · May 14, 2026 · PreprintNeuroscience