How heterogeneous thymic output and homeostatic proliferation shape naive T cell receptor clone abundance distributions
R. Dessalles, M. D'Orsogna, T. Chou
The paper quantifies how TCR-dependent heterogeneities in proliferation and immigration rates shape naive T cell clone abundance distributions, finding proliferation heterogeneity is more important than immigration heterogeneity.
bioRxiv · Jun 19, 2019 · PreprintImmunology