Polygenic Risk Scores for Prediction of Breast Cancer Risk in Women of African Ancestry: a Cross-Ancestry Approach
Guimin Gao, Fangyuan Zhao, Thomas U. Ahearn, Kathryn L. Lunetta, Melissa A. Troester, Zhaohui Du, Temidayo Olusade Ogundiran, Oladosu Akanbi Ojengbede, William J. Blot, Katherine L. Nathanson, Susan M. Domchek, Barbara Berger Nemesure, Anselm J. M. Hennis, Stefan Ambs, Julian C. McClellan, , Dezheng Huo
This paper develops polygenic risk scores for breast cancer prediction in women of African ancestry by combining African and European ancestry datasets, improving prediction accuracy.
Human Molecular Genetics · May 10, 2022Peer-reviewedGenetic & Genomic Medicine