Altered Brain Dynamics in idiopathic REM sleep behavior disorder: Implications for a continuum from prodromal to overt alpha-synucleinopathies
M. Roascio, S. H. Wang, V. Myrov, F. Siebenhuhner, R. D. Tro', P. Mattioli, F. Fama', S. D. Morbelli, M. Pardini, J. M. Palva, D. Arnaldi, G. Arnulfo
This study shows that iRBD patients exhibit altered brain dynamics, including increased excitation and reduced bistability, which correlate with disease progression and dopaminergic dysfunction.
bioRxiv · May 5, 2023 · PreprintBioengineering