Author

David E. Kling

Broad InstituteORCID 0000-0002-0624-1046Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 1 Research Focus:software / tool· 1 Approach:statistical model· 1 Research Focus:variant calling· 1 Assay:whole-exome sequencing· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Ami Levy‐Moonshine· 1 shared Benjamin M. NealeiD· 1 shared Chris Whelan· 1 shared Daniel G. MacArthuriD· 1 shared David Roazen· 1 shared Eric BanksiD· 1 shared Geraldine A. Van der AuweraiD· 1 shared Joel Thibault· 1 shared

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2018-2018 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperGenomics

Ami Levy‐Moonshine

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1 paper

Recent·Most cited

GenomicsbioRxivPreprintJul 24, 2018

✦ In-depth digest

Scaling accurate genetic variant discovery to tens of thousands of samples

Ryan E. Poplin, Valentín Ruano-Rubio, Mark A. DePristo…·Eric Banks

Per-sample assembly with gVCF output, followed by joint genotyping, lets GATK HaplotypeCaller scale linearly with cohort size while calling indels more accurately than SAMtools, UnifiedGenotyper or Platypus.

1,941 citations

humanwhole-genome sequencing