Systems BiologyProceedings of the National Academy of SciencesPeer-reviewed
NICEgame: A workflow for annotating the knowledge gaps in metabolic reconstructions, using known and hypothetical reactions
Evangelia Vayena, Anush Chiappino-Pepe, Homa MohammadiPeyhani…·Vassily Hatzimanikatis A
NICEgame identifies and resolves metabolic gaps in genome-scale models by suggesting alternative reactions and genes, improving gene essentiality predictions in E. coli.
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