Author

Tristan O. C. Kwan

Google DeepMind (United Kingdom)ORCID 0000-0002-5524-6409Unclaimed ORCID profile · follow to get notified of new preprints

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Synthetic Biology· 1

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Approach:machine learning (classical)· 1 Research Focus:protein design· 1 Assay:protein sequence· 1

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Akvilė Žemgulytė· 1 shared Alexander E. ChuiD· 1 shared Amy E. DansoniD· 1 shared Ariane MoraiD· 1 shared Ashok Thillaisundaram· 1 shared Augustin ŽídekiD· 1 shared Charles A. EmrichiD· 1 shared David La· 1 shared

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2026-2026 · peak 1/yr

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1 shared paperSynthetic Biology

Akvilė Žemgulytė

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1 paper

Recent·Most cited

Synthetic BiologybioRxivPreprintOct 5, 2026

Designing enzymes for new-to-nature chemistry and non-natural substrates with AlphaProtein Novo

Zachary Wu, Josh Abramson, Thomas Frerix…·Jue Wang

This paper introduces AlphaProtein Novo, a machine-learning pipeline for de novo enzyme design that outperforms natural sequence mining in creating enzymes for new-to-nature chemistry and substrates.

DOI 10.64898/2026.10.01.756017

protein sequencemachine learning (classical)