Genetic analysis of lung cancer reveals novel susceptibility loci and germline impact on somatic mutation burden
Aurélie AG Gabriel, Joshua Ronald Atkins, Ricardo Cortez Cardoso Penha, Karl Smith-Byrne, Valérie Gaborieau, Catherine Voegele, Behnoush Abedi‐Ardekani, Maja Milojevic, Robert Olaso, Vincent Meyer, Anne Boland, Jean‐François Deleuze, David Georgievich Zaridze, Мукерия Ануш Феликсовна, Beata Świątkowska, , James McKay
This study identifies eight novel lung cancer susceptibility loci and shows that germline variants related to smoking and DNA repair influence somatic mutation burden in lung tumors.
JNCI Journal of the National Cancer Institute · Apr 27, 2022Peer-reviewedGenetic & Genomic Medicine