Author

Thomas Karagianes

Eterna Massive Open LaboratoryORCID 0009-0004-9872-1339Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:protein structure prediction· 2 Approach:benchmark study· 1 Research Focus:benchmarking· 1 Approach:deep learning· 1 Assay:DNA methylation· 1 Assay:protein structure· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Rhiju DasiD· 2 shared Shujun HeiD· 2 shared Adamo S. MancinoiD· 1 shared Alissa M. HummeriD· 1 shared Andrew FavoriD· 1 shared Andrew KubaneyiD· 1 shared Andriy KryshtafovychiD· 1 shared Boris RudolfsiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersBiophysics

Rhiju DasORCID

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2 papers

Recent·Most cited

BiophysicsSciencePeer-reviewedAug 27, 2026

De novo design of RNA pseudoknots with deep learning

Jill Townley, Wipapat Kladwang, David A. Baker…·Rhiju Das

This paper demonstrates that deep learning can accurately design RNA pseudoknots, achieving results comparable to human experts in a competition.

5 citationstop 1%

proteomicsdeep learning

BiophysicsProteins Structure Function and BioinformaticsPeer-reviewedOct 30, 2025

✦ In-depth digest

Assessment of Nucleic Acid Structure Prediction in CASP16

Rachael C. Kretsch, Alissa M. Hummer, Shujun He…·Rhiju Das

Across 42 CASP16 nucleic acid targets, accuracy stayed tied to template availability; human experts (Vfold first) led servers and AlphaFold 3, though servers now improve on templates on average.

51 citationstop 1%

protein structureDNA methylation