Journal of Computational BiologyBioinformaticsPeer-reviewed journal article
Continuous embeddings of DNA sequencing reads, and application to metagenomics
Abstract
We propose a new model for fast classification of DNA sequences output by next generation sequencing machines. The model, which we call fastDNA, embeds DNA sequences in a vector space by learning continuous low-dimensional representations of the k-mers it contains. We show on metagenomics benchmarks that it outperforms state-of-the-art methods in terms of accuracy and scalability.
- assay: metagenomics
- research focus: benchmarking
- research focus: variant calling
- approach: deep learning
- approach: statistical model
- Citations
- 42
- FWCI
- 2.48
- Field percentile
- top 9%
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