BMC Genomic DataBioinformaticsPeer-reviewed journal article
Genomic Benchmarks: A Collection of Datasets for Genomic Sequence Classification
Katarína GrešováiD, Vlastimil MartinekiD, David Čechák, Petr ŠimečekiD, Panagiotis AlexiouiD
Abstract
In this paper, we propose a collection of curated and easily accessible sequence classification datasets in the field of genomics. The proposed collection is based on a combination of novel datasets constructed from the mining of publicly available databases and existing datasets obtained from published articles. The main aim of this effort is to create a repository for shared datasets that will make machine learning for genomics more comparable and reproducible while reducing the over-head of researchers that want to enter the field. The collection currently contains eight datasets that focus on regulatory elements (promoters, enhancers, open chromatin region) from three model organisms: human, mouse, and roundworm. A simple convolution neural network is also included in a repository and can be used as a baseline model. Benchmarks and the baseline model are distributed as the Python package genomic-benchmarks, and the code is available at https://github.com/ML-Bioinfo-CEITEC/genomic_benchmarks.
- organism: human
- organism: mouse
- organism: zebrafish
- assay: DNA methylation
- assay: whole-genome sequencing
- research focus: benchmarking
- research focus: sequence-to-function modeling
- approach: machine learning (classical)
- Citations
- 75
- FWCI
- 6.66
- Field percentile
- top 2%
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