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Scientific ReportsBioinformaticsPeer-reviewed journal article

A Look-ahead Monte Carlo Simulation Method for Improving Parental Selection in Trait Introgression

Saba MoeinizadeiD, Ye HaniD, Hieu Pham, Guiping HuiD, Lizhi WangiD

PDFDOIPreprint

Abstract

Multiple trait introgression is the process by which multiple desirable traits are converted from a donor to a recipient cultivar through backcrossing and selfing. The goal of this procedure is to recover all the attributes of the recipient cultivar, with the addition of the specified desirable traits. A crucial step in this process is the selection of parents to form new crosses. In this study, we propose a new selection approach that estimates the genetic distribution of the progeny of backcrosses after multiple generations using information of recombination events. To demonstrate the effectiveness of the proposed method, a case study has been conducted using maize data where our method is compared with state-of-the-art approaches. Simulation results suggest that the proposed method, look-ahead Monte Carlo, achieves higher probability of success than existing approaches.

Citations
17
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1.98
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top 14%

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