BioinformaticsBioinformaticsPeer-reviewed journal article
AKT: Ancestry and Kinship Toolkit
Rudy Arthur, Ole Schulz-Trieglaff, Anthony J Cox, Jared Michael O'Connell
Abstract
Ancestry and Kinship Toolkit (AKT) is a statistical genetics tool for analysing large cohorts of whole-genome sequenced samples. It can rapidly detect related samples, characterise sample ancestry, calculate correlation between variants, check Mendel consistency and perform data clustering. AKT brings together the functionality of many state-of-the-art methods, with a focus on speed and a unified interface. We believe it will be an invaluable tool for the curation of large WGS data-sets.\n\nAvailabilityThe source code is available at https://illumina.github.io/akt\n\nContactjoconnell@illumina.com, rudy.d.arthur@gmail.com
- assay: whole-genome sequencing
- research focus: variant calling
- research focus: clustering
- approach: statistical model
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