Mitochondrial sirtuin TcSir2rp3 affects TcSODA activity and oxidative stress response in Trypanosoma cruzi
L. dos Santos Moura, V. Santana Nunes, A. A. S. Gomes, A. C. de Castro Nascimento Sousa, M. R. M. Fontes, S. Schenkman, N. S. Moretti
This study shows that TcSir2rp3 modulates TcSODA activity and oxidative stress response in T. cruzi by acetylation, affecting enzyme structure and function.
bioRxiv · Sep 6, 2021Microbiology