Structural basis of promiscuous inhibition of Listeria virulence activator PrfA by oligopeptides
Tobias Hainzl, Mariela Scortti, Cecilia Lindgren, Christin Grundström, Emilia Krypotou, José A. Vázquez‐Boland, A. E. Sauer-Eriksson
The paper reveals how oligopeptides inhibit PrfA, a virulence activator in Listeria, by binding to its glutathione-binding tunnel and preventing its activation.
Cell Reports · Feb 1, 2025Peer-reviewedBiochemistry