Focal DNA hypo-methylation in cancer is mediated by transcription factors binding
D. Detilleux, Y. G. Spill, D. Balaramane, M. Weber, A. F. Bardet
The paper identifies transcription factors driving aberrant DNA methylation in cancer by analyzing The Cancer Genome Atlas data and validates their role in hypo-methylated regions.
bioRxiv · Apr 20, 2021Cancer Biology