Identifying Sequence Perturbations to an Intrinsically Disordered Protein that Determine Its Phase Separation Behavior
B. Schuster, G. L. Dignon, W. S. Tang, F. Kelley, A. K. Ranganath, C. N. Jahnke, A. G. Simpkins, R. M. Regy, D. A. Hammer, M. C. Good, J. Mittal
This study identifies sequence features of an intrinsically disordered protein that influence its phase separation behavior through computational modeling and experimental validation.
bioRxiv · Jan 6, 2020Biophysics