A. Giansanti

Mutations in disordered proteins as early indicators of nucleic acid changes triggering speciation

The paper examines how mutations in disordered proteins correlate with early nucleic acid changes during speciation, finding IDPs diverge earlier than ordered proteins.

Evolutionary forces on different flavors of intrinsic disorder in the human proteome

This study examines evolutionary forces shaping codon usage in human genes encoding structured and intrinsically disordered proteins, finding that disordered proteins experience stronger mutational bias and selection.

New perspectives into the evolutionary pressures acting on the Human intrinsically disordered proteins

This study quantifies evolutionary pressures on human genes based on protein structure, finding that intrinsically disordered proteins experience distinct mutational and selective pressures.