A. L. Loshbaugh

Comparison of Rosetta flexible-backbone computational protein design methods on binding interactions

This study compares flexible-backbone computational protein design methods in Rosetta, finding that CoupledMoves better recaptures observed sequence profiles for binding interactions than BackrubEnsemble and FastDesign.

Computational design of a modular protein sense/response system

This paper designs modular protein sensors that respond to specific small molecule inputs using a computational strategy.