Author

A. M. Graham

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 3

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Research Focus:chromatin & epigenetic regulation· 3 Approach:comparative / phylogenetic analysis· 2 Research Focus:development & morphogenesis· 2 Assay:DNA methylation· 2 Organism:multiple species· 2 Approach:statistical model· 2 Organism:zebrafish· 2 Research Focus:cell type annotation· 1

Frequent Co-Authors

J. S. Presnell· 2 shared N. L. Clark· 2 shared A. Fustukjian· 1 shared A. Michaels· 1 shared C. Cournoyer· 1 shared C. E. Furlong· 1 shared D. E. Crocker· 1 shared J. M. Jamison· 1 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersEvolutionary Biology

J. S. Presnell

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3 papers

Recent·Most cited

Reduction of Paraoxonase expression followed by inactivation across independent semiaquatic mammals suggests stepwise path to pseudogenization

A. M. Graham, J. M. Jamison, M. Bustos, C. Cournoyer, A. Michaels, J. S. Presnell, R. Richter, D. E. Crocker, A. Fustukjian, M. E. Hunter, L. D. Rea, C. E. Furlong, W. K. Meyer, N. L. Clark

The paper shows that reduced expression and inactivation of the Pon1 gene in aquatic/semiaquatic mammals precedes pseudogenization, suggesting a stepwise loss of function linked to environmental adaptation.

bioRxiv · Sep 29, 2022Evolutionary Biology

Highly Dynamic Gene Family Evolution Suggests Changing Roles for PON Genes Within Metazoa

S. A. M. Lucas, A. M. Graham, J. S. Presnell, N. L. Clark

The paper investigates the dynamic evolution of the PON gene family across metazoa, identifying multiple expansion and loss events in different lineages and suggesting environmental factors like pathogen infection and oxidative stress as drivers.

bioRxiv · May 17, 2022Evolutionary Biology

Dynamic evolution of the major transcription factor DNA binding domain, and protein-protein interaction families during the evolution of the avian lineage

A. M. Graham, J. Presnell

The paper analyzes DNA binding and protein-protein interaction domain families in bird and reptile genomes to assess their role in phenotypic diversity, finding a general loss of domain families in birds.

bioRxiv · Jul 25, 2019 · PreprintEvolutionary Biology