Helix 8 in chemotactic receptors of the complement system.
S. Wisniewski, P. Dragan, A. Makal, D. Latek
The paper analyzes the structural and dynamic properties of C5aR1, a chemotactic receptor, focusing on the role of inverted helix H8 in its activation mechanism and signaling differences compared to its homolog C5aR2.
bioRxiv · Mar 7, 2022Immunology