Protein citrullination was introduced into animals by horizontal gene transfer from cyanobacteria
T. F. Cummings, K. Gori, L. Sanchez-Pulido, G. Gavriilidis, D. Moi, A. R. Wilson, E. P. Murchison, C. Dessimoz, C. Ponting, M. A. Christophorou
This study identifies horizontal gene transfer of citrullinating enzymes from cyanobacteria to animals, revealing an ancient origin of a key post-translational modification.
bioRxiv · Jun 13, 2020Evolutionary Biology