Transcriptional competition biases the effects of second messengers in Escherichia coli
A. Ripamonti, Milan Lacassin, Rossana Droghetti, Gregory Bokinsky, Marco Cosentino Lagomarsino
The paper shows that second messengers in E. coli affect gene expression through transcriptional competition, reshaping proteome allocation beyond individual regulatory effects.
Cell Systems · May 14, 2026Peer-reviewedSystems Biology