Synergy of calcium release site determinants in control of calcium release events in cardiac myocytes
B. Iaparov, I. Zahradnik, A. S. Moskvin, A. Zahradnikova
The paper uses in silico models to study how geometric factors of RyR arrangement influence calcium release events in cardiac myocytes, finding that CRE characteristics follow a mass action law based on RyR vicinity and single-channel current.
bioRxiv · Aug 26, 2020 · PreprintBiophysics