Formalin fixation and paraffin embedding interfere with preservation of optical metabolic assessments based on endogenous NAD(P)H and FAD two photon excited fluorescence
A. Sanchez-Hernandez, C. M. Polleys, I. Georgakoudi
This study shows that formalin fixation and paraffin embedding alter NAD(P)H and FAD two-photon fluorescence metrics in murine tissues, affecting optical metabolic assessments.
bioRxiv · Jun 16, 2023 · PreprintBioengineering