Author

A. Sandoval-Perez

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Biology Disciplines

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Biophysics· 1

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Approach:deep learning· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1 Approach:statistical model· 1

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C. Aponte-Santamaria· 1 shared V. Mejia-Restrepo· 1 shared

Activity by Year

2022-2022 · peak 1/yr

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1 shared paperBiophysics

C. Aponte-Santamaria

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1 paper

Recent·Most cited

Thermodynamic stabilization of the von Willebrand Factor A1 domain due to loss-of-function disease-related mutations.

A. Sandoval-Perez, V. Mejia-Restrepo, C. Aponte-Santamaria

This study investigates how mutations G1324A and G1324S in the vWF A1 domain affect its thermodynamic stability and conformational flexibility, leading to reduced platelet adhesion in type 2M von Willebrand disease.

bioRxiv · Mar 10, 2022Biophysics