Senescence and entrenchment in evolution of amino acid sites
A. V. Stolyarova, E. Nabieva, V. V. Ptushenko, A. V. Favorov, A. V. Popova, A. D. Neverov, G. A. Bazykin
The paper distinguishes between entrenchment and senescence in amino acid site evolution, showing entrenchment dominates in negatively selected sites while senescence occurs in positively selected sites.
bioRxiv · Oct 8, 2019Evolutionary Biology