Author

Adithya Sagar

Cornell University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Systems Biology· 3

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Jeffrey D. VarneriD· 3 shared Rachel LeCoveriD· 2 shared Andrew YeniD· 1 shared Christine A. ShoemakeriD· 1 shared David L. DaiiD· 1 shared Holly A. Jensen· 1 shared Johanna Congleton· 1 shared Katharine V. Rogers· 1 shared

Activity by Year

2017-2018 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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3 shared papersSystems Biology

Jeffrey D. VarnerORCID

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Author profile →

3 papers

Recent·Most cited

Dynamic Optimization with Particle Swarms (DOPS): A meta-heuristic for parameter estimation in biochemical models

Adithya Sagar, Rachel LeCover, Christine A. Shoemaker, Jeffrey D. Varner

This paper introduces DOPS, a hybrid meta-heuristic for parameter estimation in biochemical models, which outperforms existing methods on test functions and real-world models.

BMC Systems Biology · Oct 12, 2018Peer-reviewedSystems Biology

Reduced order modeling and analysis of the human complement system

Adithya Sagar, Wei Dai, Mason Minot, Rachel LeCover, Jeffrey D. Varner

The paper develops a reduced order mathematical model of the human complement system that is predictive and computationally efficient, showing that multiple therapeutic targets are needed to disrupt complement activation.

PLoS ONE · Nov 20, 2017Peer-reviewedSystems Biology

An Effective Model Of The Retinoic Acid Induced HL-60 Differentiation Program

Ryan A. Tasseff, Holly A. Jensen, Johanna Congleton, David L. Dai, Katharine V. Rogers, Adithya Sagar, Rodica Petruta Bunaciu, Andrew Yen, Jeffrey D. Varner

This study develops an effective model of ATRA-induced HL-60 differentiation, identifying key feedback mechanisms and critical genes involved in the process.

Scientific Reports · Oct 24, 2017Peer-reviewedSystems Biology