How Phosphorylation of alpha/beta-Tubulin Perturbs Microtubule Structure: A Computational Study
Annemarie Ianos, Ahmed Osman, Baofu Qiao, Susan A. Rotenberg
This study uses molecular dynamics simulations to show how phosphorylation of alpha or beta-tubulin alters microtubule structure and affects GTP hydrolysis and dynamic instability.
Journal of Biological Chemistry · Aug 26, 2026Peer-reviewedBiochemistry