Lipid Desaturation Regulates the Balance between Self-renewal and Differentiation in Mouse Blastocyst-derived Stem Cells
Chanchal Thomas Mannully, Reut Bruck‐Haimson, Anish Zacharia, Paul Orih, Alaa Shehadeh, Daniel Menezes Saidemberg, Natalya M. Kogan, Sivan Alfandary, Raphael Serruya, Arie Dagan, Isabelle Petit, Arieh Moussaieff
The paper identifies lipid desaturation as a metabolic regulator of self-renewal and differentiation in mouse blastocyst-derived stem cells, showing distinct effects on embryonic stem cells (ESCs) and trophoblast stem cells (TSCs).
Cell Death and Disease · Dec 7, 2022Peer-reviewedDevelopmental Biology