Birth by Cesarean Section Remodels Neonatal Brain Barriers and Associated Immune and Metabolic Pathways in Mice
Valentine Turpin, Jennifer Morael, Alexandre Jean Claude Cergneux, H. Blair, Elisa Cintado, Atreye Majumdar, Carmen Tessier, Lorena Morales, Emily G. Knox, Anna Ratsika, Katherine E. Guzzetta, Ana Paula Ventura‐Silva, Jennifer Shearer, Neil J. Loftus, Emily Grace Armitage, , María R. Aburto
This study shows that cesarean section in mice alters brain barrier function, immune profiles, and metabolism in the neonatal brain, highlighting birth mode's impact on early brain development.
bioRxiv · Jun 18, 2026 · PreprintNeuroscience