Clinically Important sex differences in GBM biology revealed by analysis of male and female imaging, transcriptome and survival data
Wei Yang, Nicole M. Warrington, Sara J. Taylor, Eduardo Carrasco, Kyle W. Singleton, Ningying Wu, Justin D. Lathia, Michael E. Berens, Albert H. Kim, Jill S. Barnholtz-Sloan, Kristin R. Swanson, Jingqin Luo, Joshua B Rubin
The paper identifies sex-specific molecular subtypes of glioblastoma and shows that temozolomide is more effective in female patients, suggesting sex-specific treatment approaches could improve outcomes.
bioRxiv · Dec 12, 2017 · PreprintCancer Biology