Tube to Tumour: an integrative epigenomic analysis of DNA methylation in high-grade serous ovarian cancer and precursor serous tubal intraepithelial carcinoma
Asia Jordan, Aideen McCabe, Alejandra Rodriguez, Kellie A. Dean, Sudipto Das, Antoinette Sabrina Perry
This study identifies conserved DNA methylation patterns and gene expression changes in STIC and HGSOC, revealing epigenetic remodelling that may drive invasion and offer early detection opportunities.
bioRxiv · Jun 12, 2026 · PreprintCancer Biology