Impaired yolk sac NAD metabolism disrupts murine embryogenesis with relevance to human birth defects
Kayleigh Bozon, Hartmut Cuny, Delicia Z Sheng, Ella M. M. A. Martin, Alena Sipka, Paul E. Young, David T. Humphreys, Sally L. Dunwoodie
The paper identifies impaired NAD metabolism in the yolk sac as a cause of congenital malformations in mice, with implications for human birth defects.
eLife · Feb 26, 2025Peer-reviewedDevelopmental Biology