Ultra-sensitive mutation detection and genome-wide DNA copy number reconstruction by error corrected circulating tumour DNA sequencing
Sonia Mansukhani, Louise J. Barber, Dimitrios Kleftogiannis, Sing Yu Moorcraft, Michael Davidson, Andrew Woolston, Paula Proszek, Beatrice L. Griffiths, Kerry Fenwick, Bram Herman, Nik Matthews, Ben O’Leary, Sanna Hulkki Wilson, David González de Castro, Anisha Patel, , Marco Gerlinger
This paper develops an error-corrected cfDNA sequencing method for highly sensitive mutation detection and genome-wide copy number reconstruction in metastatic colorectal cancer.
Clinical Chemistry · Aug 27, 2018Peer-reviewedGenomics