Author

Alex E. Lash

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Biology Disciplines

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Bioinformatics· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 1 Organism:human· 1 Organism:multiple species· 1 Assay:protein structure· 1 Approach:statistical model· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Christian L. Mueller· 1 shared Evan H. Baugh· 1 shared Natalia Volfovsky· 1 shared Rebecca F. AlfordiD· 1 shared Richard BonneauiD· 1 shared Riley Simmons-Edler· 1 shared

Activity by Year

2016-2016 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 15 mutual co-author links

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1 shared paperBioinformatics

Christian L. Mueller

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1 paper

Recent·Most cited

Robust Classification of Protein Variation Using Structural Modeling and Large-Scale Data Integration

Evan H. Baugh, Riley Simmons-Edler, Christian L. Mueller, Rebecca F. Alford, Natalia Volfovsky, Alex E. Lash, Richard Bonneau

VIPUR integrates sequence and structural modeling to classify protein variants, showing improved accuracy and interpretability in predicting deleterious mutations across organisms and diseases.

Nucleic Acids Research · Feb 28, 2016Peer-reviewedBioinformatics