Insights to HIV-1 coreceptor usage by estimating HLA adaptation with Bayesian generalized linear mixed models
Anna Hake, Anja Germann, Corena de Beer, Alexander Thielen, Martin Däumer, Wolfgang Preiser, Hagen von Briesen, Nico Pfeifer
This paper develops Bayesian generalized linear mixed models to estimate HLA adaptation in HIV-1 and finds that CXCR4-using variants are more adapted than CCR5-using variants.
PLoS Computational Biology · Dec 21, 2023Peer-reviewedBioinformatics