Author

Alexandre V Morozov

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Biology Disciplines

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Biophysics· 1 Evolutionary Biology· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Approach:biophysical modeling· 2 Research Focus:protein folding & dynamics· 2 Approach:statistical model· 2 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1 Assay:proteomics· 1

Frequent Co-Authors

Constantin D Malliaris· 1 shared George Locke· 1 shared Michael Manhart· 1 shared Pavel Khromov· 1 shared

Activity by Year

2014-2016 · peak 1/yr

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4 top collaborators · 1 mutual co-author link

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1 shared paperGenetics

Constantin D Malliaris

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3 papers

Recent·Most cited

Generalization of the Ewens sampling formula to arbitrary fitness landscapes

Pavel Khromov, Constantin D Malliaris, Alexandre V Morozov

This paper extends the Ewens sampling formula to arbitrary fitness landscapes, showing that steady-state allelic diversity can infer selection coefficients from sequence data.

bioRxiv · Jul 21, 2016Genetics

A biophysical approach to predicting protein-DNA binding energetics

George Locke, Alexandre V Morozov

This paper introduces BindSter, a biophysical model for predicting protein-DNA binding specificities, and finds that simpler models perform better than previous approaches.

Genetics · Aug 1, 2015Peer-reviewedBiophysics

Protein folding and binding can emerge as evolutionary spandrels through structural coupling

Michael Manhart, Alexandre V Morozov

The paper shows how protein folding and binding can evolve as spandrels, even without fitness benefits, through structural coupling and random mutations.

bioRxiv · Aug 20, 2014Evolutionary Biology