Label-free assessment of red blood cell storage lesions by deep learning
Minh Doan, Joseph A. Sebastian, Juan Carlos Caicedo, Stefanie Siegert, Aline Roch, Tracey R. Turner, Olga O. Mykhailova, Ruben N. Pinto, Claire McQuin, Allen Goodman, Michael J. Parsons, Olaf Wolkenhauer A, Holger Hennig, Shantanu Singh, Anne Wilson, , Anne Elizabeth Carpenter
This study uses deep learning and label-free imaging flow cytometry to classify red blood cell morphologies during storage, achieving 90% accuracy and predicting expiration dates based on morphological changes.
Proceedings of the National Academy of Sciences · Aug 24, 2020Peer-reviewedBioinformatics