Matrix Metalloproteinase Response to Acute Resistance Exercise is Altered in Osteoarthritic Adults with Increased Muscle Collagen and PDGFRα+ Mesenchymal Cells
Allyson M. Schweitzer, Max J. Abercrombie, Matthew D. Fliss, Aneesha Thouli, Alix P Wells, Lucas Wiens, Abaigeal L. Kelso, Cameron J. Mitchell
This study examines how MMPs respond to resistance exercise in knee OA patients, finding impaired ECM remodeling and altered PDGFR+ mesenchymal and satellite cell dynamics.
bioRxiv · Oct 16, 2026 · PreprintPhysiology