HistoGWAS: An AI-enabled Framework for Automated Genetic Analysis of Tissue Phenotypes in Histology Cohorts
Shubham Chaudhary, Almut Voigts, Michael D. Bereket, Matthew L. Albert, Kristina Schwamborn, Eleftheria Zeggini, Francesco Paolo Casale
HistoGWAS performs genome-wide association studies on histological traits using AI tools and variance component models, identifying four genome-wide significant loci in GTEx data.
bioRxiv · Jun 9, 2024 · PreprintGenetics