Resting-state functional dynamics alterations relate to plasma amyloid markers and explain memory impairments in the TgF344-AD model of Alzheimer's disease
Alya Al-Awlaqi, Lori Berckmans, Sam De Waegenaere, Sarah Vanherle, Joseph C. Griffis, Ilse Dewachter, Marleen Verhoye, Mohit H. Adhikari
The paper examines resting-state fMRI dynamics in a rat model of Alzheimer's disease, linking functional changes to amyloid levels and memory impairments, with better predictive power from pre-plaque stage CAPs.
bioRxiv · Jun 1, 2025 · PreprintNeuroscience