Distinguishing Signal from Noise: Understanding Patterns of Non-Detections to Inform Accurate Quantitative Metabarcoding
Zachary J. Gold, Andrew Olaf Shelton, Helen R. Casendino, Joe Duprey, Ramón Gallego, Amy Van Cise, Mary Fisher, Alexander J. Jensen, Erin R. D'Agnese, Elizabeth Andruszkiewicz Allan, Ana Ramón‐Laca, Maya Garber‐Yonts, Michaela Labare, Kim M. Parsons, Ryan P. Kelly
This study investigates non-detections in metabarcoding data to improve quantitative accuracy by modeling amplification biases and stochastic sampling effects.
PLoS ONE · May 11, 2023Peer-reviewedMolecular Biology