Deciphering the transcriptomic landscape of pyrazinamide resistance in Mycobacterium tuberculosis
Ananthi Rajendran, Ahmed Kabir Refaya, Kannan Palaniyandi
This study compares transcriptomic responses of a pyrazinamide-resistant Mycobacterium tuberculosis clinical strain and a drug-susceptible strain, identifying mutation-driven gene expression changes and cross-resistance mechanisms.
bioRxiv · Oct 13, 2025 · PreprintMicrobiology