Multi-context genetic modeling of transcriptional regulation resolves novel disease loci
Michael Thompson, Mary Grace Gordon, Andrew C. Lu, Anchit Tandon, Eran Halperin, Alexander Gusev, Chun Ye, Brunilda Balliu, Noah Zaitlen
The paper introduces CONTENT, a method for multi-context genetic modeling of transcriptional regulation, which improves power and discovers more gene-phenotype associations in TWAS.
Nature Communications · Sep 28, 2022Peer-reviewedGenomics