Large-scale analysis of DNA methylation identifies cellular alterations in blood from psychosis patients and molecular biomarkers of treatment-resistant schizophrenia.
Eilis J. Hannon, Emma Louise Dempster, Georgina Mansell, Joe Burrage, Nicholas James Bass, Marc M. Bohlken, Aiden Peter Corvin, Charles J. C. Curtis, David W. Dempster, Marta Di Forta, Timothy G. Dinan, Gary J Donohoe, Fiona Gaughran, Michael Gill, Amy L. Gillespie, , Jonathan S. Mill
This study identifies DNA methylation changes in blood samples from psychosis patients, including treatment-resistant schizophrenia, and links them to biological age, smoking, and cellular composition.
bioRxiv · Apr 5, 2020 · PreprintGenomics