Absolute Winding Number Differentiates Spatial Navigation Strategies with Genetic Risk for Alzheimer's Disease
Alexandra Badea, Didong Li, Andrei R. Niculescu, Robert J. Anderson, Jacques Andrew Stout, Christina L. Williams, Carol A. Colton, Nobuyo Maeda, David B. Dunson
The paper introduces a new metric, absolute winding number, to differentiate spatial navigation strategies in mice with different APOE alleles, revealing genotype and sex differences linked to Alzheimer's disease risk.
bioRxiv · Feb 4, 2022 · PreprintNeuroscience